Application for NGFN-2
KG: Infection and Inflammation

SIPAGE
"From Pathogen-Induced Signatures to Therapeutic Target Gens: Comparative and Functional Analysis of the Inflammatory Response in Health and Disease"
Relevant patents filed or issued over the past five years

Professor Trinad Chakraborty

TGC method for inducting targeted somatic transgenesis.
Von Eichel-Streiber, Chr.; Chakraborty, T. CA000002315216A1, 17.06.1999, DE000019754938A1, 24.06.1999, WO001999029884A3, 12.08.1999, EP000001023453A2, 02.08.2000, AU000000751517B, 15.08.2002

Listeria monocytogenes genome, polypeptides and uses.
Dominguez-Bernal, G.; Glaser, P.; Vazquez-Boland, J.A; Perez-Diaz, J.C.; Entian, K.-D.; Berche, P.; Baquero, F.; Hauf, J.; Hain, T. ; Gomez-Lopez, N. ; Kaerst, U.; Garcia del Portillo, F., Chakraborty, T.; Chetouani, F.; Domann, E.; Maduenio, E.; Dussurget, O.; Kreft, J.; Goebel, W. ; Rose, M.; Kunst, F.; Ng, E.; De Pablos, B.; Cossart, P.; Nedjari, H.; Wehland, J.; Kuhn, M.; Daniels, J.; Buchrieser, C.; Garrido-Garcia, P.; Charbit, A.; Couve, E.; Frangeul, L.; Amend, A.; Tierrez-Martinez, A.; Durant, L.; Fsihi, H.; Rusniok, Chr.; Dehoux, P., Voss, H. CA000002404988A1, 18.10.2001

Method for the determination of pathogenic Listeria bacteria.
Chakraborty, T.; Goebel, W.; Notermans, SHW. CA000002025566C, 18.06.2002

Screening Assay zur Bewertung des Potentials von Verbindungen, die gegen eine Infektion mit Listeria monocytogenes wirksam sind.
Heinz, D.; Wehland, J; Schubert, W.-D.; Domann, E., Chakraborty, T. DE000010218396A1. 17.07.2003.

Recombinant attenuated Listerias for immunotherapy.
Schadendorf, D.; Paschen, A.; Chakraborty, T.; Domann, E.
WO002001027295A1, 19.04.2001, DE000019949594A1 26.04.2001, EP000001228224A1 07.08.2002.

Attenuated Salmonella strain used as a vehicle for oral immunization.
Darji, A.; Guzm, N., Carlos, C.; Timmis, K.; Wehland, J.; Weiss, S.; Gerstel, B.; Chakraborty, T.; Wachholz, P. EP000000977874A1, 09.02.2000, US020030180320A1, 25.09.2003.

Detection of diarrhoeogenic E. coli germs.
Chakraborty, T.; Teigelkamp, St.; Ebel, F.; Scheefers-Borchel, U.; Scheefers, H.
DE 200101174, 04.10.2001, WO002001073440A3, 30.05.2002

 

Professor Ingo Autenrieth

Patent Nr. 00985048.8-2402 (EPA) 16.11.2000 "Test von Mikroorganismen" DE 19955303. Heesemann, Autenrieth et al
Patent Nr. 103 51 627.1 November 2003, "Modulation der Angiogenese durch Bartonella henselae. Kempf, Autenrieth
PCT/EP99/03527 WO/Wwvo (2003). Haas, R. and Trebesius, K.-H. Nachweis von Antiobiotikaresistenzen in Mikroorganismen Europäische Patentanmeldung
Europäisches Patent 12208P EP-WO/Wwgo (2003) Haas, R et al. Verfahren zur Identifizierung sekretorischer Gene aus Helicobacter pylori

Professor Hermann Wagner
No. Title

EP 97 10 1019.4
PCT/EP98/00367
US Serial No. 09/355 254

Pharmaceutical compositions comprising a polynucleotide and optionally an antigen especially for vaccination
PCT/IB99/01285US Serial No. 09/241 653 Methods for regulating hematopoiesis using CpG-Oligonucleotides
PCT/EP/9906502US Serial No. 09/786 436 G-motif oligonucleotides and uses thereof
US Serial No.10/212 133 Methods and compositions relating to plasmacytoid dendritic cells
EP00 128 634.3 Reversible MHC multimer staining for functional purification of antigen-specific T-cells
US Serial No.09/594.987 Process for high throughput screening of CpG-based immuno-agonist/antagonist
US Serial No. 60/396 432 Use of CpG nucleic acids in prion disease
US Serial No. 10/407 952 Immunostimulatory G,U-Containing oligoribonucleotides
new application Methods and products for enhancing immune responses using Imidazoquinoline compounds
new application Poly-D as carrier platform for antigen and immunostimulatory agonist and antagonist
new application Cell-free methods for identifying compounds that affect toll-like receptor 9 (TLS9) signaling

 

Professor Rudolf Balling


Reversible MHC multimers (Streptamers) - Dirk H. Busch and H. Wagner


Dr. Thomas Häupl

1. Häupl, T.; Ungethüm, U.; Bläß, S. 2002; Werkzeuge zur Diagnostik, molekularen Definition und Therapieentwicklung chronischer entzündlicher Gelenkerkrankungen; DE000010127572A1
2. Stuhlmüller, B.; Häupl, T. 2003; Nucleic acid array; EP000001310567A2
3. Stuhlmüller, B.; Häupl, T.; Kiesslich, O.; Burmester, G. R. 2003; Nukleinsäure-Array; DE000010155600A1
4. Paulitschke, M.; Bernstein, T.; Häupl, T.; 2000; Versatile cell and tissue culture chamber with improved sealing and bubble exclusion; DE000019817524C1
5. Häupl, T.; Kaps, C.; Sittinger, M.; Smolian, H. 2002; In vitro Zellinteraktionskultursystem für Medikamententestung und -Entwicklung; DE000010105420A1
6. Sittinger, M.; Schultz, O.; Burmester, G. R.; Häupl, T. 2000; Artificial tissues, methods for the production and the use thereof; US000006143501A
7. Häupl, T.; Kaps, C.; Sittinger, M.; Smolian, H. 2002; An in vitro cell interaction culture system for testing and developing medicaments; WO002002061420A3